Hyperglycaemia-induced reciprocal changes in miR-30c and PAI-1 expression in platelets
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چکیده
منابع مشابه
Hyperglycaemia-induced reciprocal changes in miR-30c and PAI-1 expression in platelets
Type 2 diabetic mellitus (DM2) is associated with accelerated thrombotic complications and is characterized by high levels of plasminogen activator inhibitor-1 (PAI-1). Recent studies show that human platelets have high levels of miR-30c and synthesize considerable active PAI-1. The underlying mechanism of how PAI-1 expression is upregulated in DM2 is poorly understood. We now report that hyper...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2016
ISSN: 2045-2322
DOI: 10.1038/srep36687